Molecular Hydrogen: The Newest and Greatest Nutritional Discovery In My Lifetime

by ProfKeith

It’s one of the biggest shocks since the discovery of vitamins… Molecular hydrogen.

What’s Prof. talking about now? Let me back up and explain.

We all know the antioxidant story… Free radicals or “reactive oxygen species” (ROS) are extremely damaging to our tissues. So we eat fresh color-rich foods and take protective substances called “antioxidants” which protect us from this damage; we stay healthy; we live longer, right?

Well, not quite, as it happens.

Yes, it’s true that ROS damage our tissues. There’s molecular oxygen (O2), superoxide (charged oxygen radical), triatomic oxygen (ozone), the hydroxyl radical (OH-) and the peroxide radical (-H2O2). They are not all as bad as each other. The hydroxyl radical (OH-) is by far the worst.

The hydroxyl radical can damage virtually all types of macromolecules: carbohydrates, nucleic acids (mutations), lipids (lipid peroxidation), and amino acids.

The so-called superoxide radical is not, in truth, as active or damaging as the basic oxygen molecule, despite its name!

Peroxide ion is generated briefly by certain white cells, to damage microbes before ingesting them. Only out of place, it is potentially harmful to us.

We have special powerful antioxidant enzymes to help protect us: superoxide dismutase, you may have heard of, inactivates the superoxide radical; catalase removes peroxides. Unfortunately, unlike these two, the hydroxyl radical cannot be eliminated by an enzymatic reaction.

That’s a problem in itself. But that’s as far as naïve scientists and “nutritionists” got, until recently.

Redox Signaling

We now realize we have been missing a piece of the puzzle. The truth is that not all ROS are bad or, more exactly, that we need small amounts of ROS present, which will functions as signalers.

It’s an aspect of a system called the REDOX signaling pathway (Red-Ox stands for reduction and oxidation). It’s a very important defense pathway. We need some ROS free radicals to get the antioxidant mechanisms in our bodies to function properly. Think of it like “bitters” in your cocktail, to get the digestive juices flowing, ready for a good meal!

In fact, there may have been more than a germ of truth in those papers that suggested that maybe taking antioxidants was bad for our health. They could be VERY bad for our health—yes, even earlier death—if we took too many. It wasn’t just a cover up conspiracy; there was some science behind it.1

Anyway, we’ve moved on. I can summarize the new understanding in one sentence: hydroxyl ions are very bad still, but the others we shouldn’t eradicate.

Can we selectively knock out the deadly hydroxyl ions, without harming the good guys… superoxide and peroxide, etc?

You bet (come on, why else would I be writing this!)

The Answer Is: Molecular Hydrogen

The answer is the commonest substance in the universe, hydrogen. In fact hydrogen IS 90% of all atoms in the cosmos, right on down to the solar system! Moreover, hydrogen lays claim to more than two-thirds of all the atoms in the human body.

Not the commonly discussed form called hydrogen ions, which give us our phenomenon of acidity and alkalinity (the more hydrogen ions, the more acid).

I’m talking of hydrogen gas, you know, the stuff that burns up airships! Hydrogen (symbol H) likes to hang our in pairs, hence H2 . We call this “molecular hydrogen”, because a set of two or more atoms is called a molecule. Right?


Molecular hydrogen is a wonderful vacuum cleaner for hydroxyl ions! In fact, even duffers at school can get this: H2 + 2OH = 2H2O. In other words water!

If only we could flood our bodies with this molecular hydrogen, we could stay healthy and live longer. Great. Be patient, I’m coming to that…

More About Lifestyle First

Despite having some beneficial activities in small quantities, reactive oxygen species can clearly be toxic to cells. By definition, radicals possess an unpaired electron, which makes them highly reactive and thereby able to damage all biological molecules, including lipids, proteins, and nucleic acids (DNA etc.)

Persistent oxidative stress is one of the major causes of most lifestyle-related diseases, cancer and the aging process. Acute oxidative stress directly causes serious damage to tissues. Despite the clinical importance of oxidative damage, antioxidants have been of limited therapeutic success, though eating lots of brightly colored fresh foods has never harmed anybody.

One of the best-known toxic effects of oxygen radicals is damage to cellular membranes (plasma, mitochondrial and endomembrane systems), which is initiated by a process known as lipid peroxidation.

Mitochondria, the small intracellular structures that generate energy for the cell, are a major site of oxidative stress. When they go, we go. We suffer immense fatigue and rapid aging. It could be said that you are as old as your mitochondria!

Acute oxidative stress also causes serious damage to other tissues, and persistent oxidative stress is one of the causes of many common diseases, cancer and the aging process; however, there has been little success in developing an effective antioxidant with no side effect.

Until now, that is. Molecular hydrogen has been shown to be excellent as a powerful and effective antioxidant for medical applications. Nobody is more surprised than me.

Molecular hydrogen has a number of advantages as a potential antioxidant: it is a tiny atom and rapidly diffuses into tissues and cells throughout the body. It is mild enough neither to disturb redox signaling reactions nor to affect reactive oxygen species (ROS) that function in cell signaling, thereby, there should be little adverse effects of consuming H2.

300 Papers Published on the Benefits…

In fact, there are now over 300 papers published in peer-reviewed journals demonstrating clearly the true health benefits of molecular hydrogen.

Since the publication of the first H2 paper in Nature Medicine in 2007, the biological effects of H2 have been confirmed2 by the publication of more than 38 diseases, physiological states and clinical tests in leading biological/medical journals, and several groups have started clinical examinations.

Moreover, H2 shows not only effects against oxidative stress, but also various anti-inflammatory and anti-allergic effects. H2 regulates various gene expressions and even triggers more of the body’s own antioxidant mechanisms.

It’s worth repeating: emerging science shows that molecular hydrogen protects us against the deadly hydroxyl radical, while leaving undamaged the other oxygen radicals that are needed for physiological signaling.3

How Do We Take It?

There are several methods to ingest or consume H2, including inhaling hydrogen gas, drinking H2-dissolved water (hydrogen water), taking a hydrogen bath, injecting H2-dissolved saline IV (hydrogen saline), dropping hydrogen saline onto the eye, and even increasing the production of intestinal H2  by bacteria.

But simplest by far is to take Active H2 from Purative. Drop a tablet into a bottle of spring water, screw on the cap while it dissolves and fizzes, then swallow the lot (fairly quickly, so you get the full benefit).

Doing this once a day approximates the dose used in the hydrogen therapy research. This literally floods the body—every nook and cranny—with free-radical quenching hydrogen.

Safe? You kidding. Because hydrogen is so prevalent in your body already, a rush of extra poses no threat. It’s a completely natural molecule.

I’m going to talk more about this in the next email but meantime, if you are convinced already, follow the links below to purchase your supply. You can try it for $60 and make up your mind. I feel an immediate rush when I take Active H2 and an energy zing. I can’t promise everyone gets that, but remember I’m 70 this year. I need an energy boost now and then!

Sportsters and gym junkies will LOVE this stuff. Give it a try.

US Orders

International Orders

Buy 3 Bottles – Save 10% & Free Shipping!


1. Hackam DG. Review: antioxidant supplements for primary and secondary prevention do not decrease mortality. ACP J Club. 2007;147:4

2. Ohsawa et al., Nat. Med. 13 (2007) 688-694

3. Ohsawa, I., Ishikawa, M., Takahashi, K., Watanabe, M., Nishimaki, K., Yamagata, K., Katsura, K., Katayama, Y., Asoh, S., Ohta, S. (2007). Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med Nature Medicine, 13(6), 688-694.


* These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure, or prevent any disease.

The products offered on this site are not intended to diagnose, treat, cure or prevent any disease. You should always ask your doctor before using any products.

You may also like:

Comments on this entry are closed.